Three-year-old development: The relationship of child health and parenting stress to neurocognition.

Purpose: This study examined parenting stress and child special healthcare needs to child neurocognitive development (NCD).

Design And Methods: This secondary analysis used data from the primary study, a longitudinal cohort study of mother-child dyads. Multivariable regression models examined the associations between parenting stress and child special healthcare needs with NCD.

Experimental medicine study with stabilised native-like HIV-1 Env immunogens drives long-term antibody responses, but lacks neutralising breadth.

Background: We report findings from an experimental medicine study of rationally designed prefusion stabilised native-like HIV envelope glycoprotein (Env) immunogens, representative of global circulating strains, delivered by sequential intramuscular injection.

Methods: Healthy adult volunteers were enrolled into one of five groups (A to E) each receiving a different schedule of one of two consensus Env immunogens (ConM SOSIP, ConS UFO, either unmodified or stabilised by chemical cross-linking, followed by a boost with two mosaic Env immunogens (Mos3.1 and Mos3.

A high-resolution in situ X-ray diffraction study of mineral transitions due to post-hydration heating in CM chondrite meteorites.

Abstract: The effects of post-hydration heating over a broad range of temperatures are evident in many Mighei-like carbonaceous (CM) chondrites as a variety of mineral transitions. To better understand these processes and how a CM chondrite's starting composition may have affected them, we experimentally heated two meteorites with different degrees of aqueous alteration, Allan Hills 83100 and Murchison, at 25 °C temperature steps from 200 °C to 950 °C and 300 °C to 750 °C, respectively. During heating, synchrotron in situ X-ray diffraction patterns were collected.

Carer Outcomes From a Residential Treatment Service for Eating Disorders.

Objective: Eating disorders often result in distress, relationship impairment, and emotional, social, and financial burden for family members and other loved ones. However, carer outcomes from eating disorder treatment are under-researched, particularly residential settings. This study aimed to examine carer outcomes from a transdiagnostic residential service for eating disorders, which included therapist-led psychoeducation and peer support for carers.

A Decade of Achievements: International Society of Paediatric Oncology Baseline Nursing Standards.

The six International Society of Paediatric Oncology (SIOP) Baseline Nursing Standards provide the first evidence-based framework for assessing and improving pediatric oncology nursing practice settings in low-, middle-, and high-income countries. Over the past 10 years, the standards have been translated to six languages, endorsed by 13 organizations, surveyed at 101 hospitals in 54 countries, and initiatives have been documented at over 63 institutions in 31 countries. Going forward, the SIOP Nursing Network's Baseline Standards Special Interest Group has established a 5-year strategic plan to guide advocacy, research, and standards implementation through global multidisciplinary collaboration.