Publications by authors named "S Etemad-Moghadam"
Article Synopsis
- Dental caries is a widespread yet preventable oral health issue, and biotics (including probiotics, prebiotics, symbiotics, and postbiotics) are suggested as affordable prevention strategies.
- A review analyzed research from 2012 onward, revealing that while studies confirm probiotics can reduce harmful bacteria and increase pH levels in the mouth, more investigation is needed to fully understand how biotics work against cavities.
- The combination of different types of biotics shows promise in caries prevention, but further studies are essential to refine their application and assess the effectiveness of postbiotics.
Oral mucositis is a complication of chemo/radiotherapy. To assess the impact of various power levels of diode-laser on the survival and expression of apoptosis-related genes in oral cancer cells, it is crucial to consider the potential existence of malignant cells within the treatment region and the reliance of laser effectiveness on its specific characteristics. Cal-27 cells were cultivated and exposed to a 660 nm-diode-laser at power levels of 20, 40, and 80 mW, alongside non-irradiated control cells.
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- Leukemia remains a widespread health issue, prompting research into alternative therapies like probiotics, particularly Lactobacillus species, for their potential anticancer effects.
- The study focused on postbiotic mediators (PMs) from Lactobacillus rhamnosus GG and Lactobacillus reuteri, testing their impact on acute lymphoblastic leukemia (ALL) cells and healthy blood cells using various assays.
- Results indicated that PMs significantly reduced viability in ALL cells and increased apoptosis, suggesting their anticancer properties; however, gene expression analysis did not show significant differences in key apoptotic genes, highlighting the need for further research.
The pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP) family has been found to have both tumor-suppressor and oncogenic properties across various types and locations of cancer. Given that PHLPP has not been previously studied in oral squamous cell carcinoma (SCC), we conducted an assessment of the expression of both its isoforms in oral SCC tissues and cell lines and compared these findings to their corresponding normal counterparts. In addition, we assessed the relationship between PHLPP and clinicopathological factors and patient survival.
View Article and Find Full Text PDFHepatic osteodystrophy, a prevalent manifestation of metabolic bone disease, can arise in the context of chronic liver disease. The THBS1-eNOS-NO signaling pathway plays a pivotal role in the maturation of osteoclast precursors. This study aimed to investigate the impact of Naltrexone (NTX) on bone loss by examining the THBS1-eNOS-NO signaling pathways in bile duct ligated (BDL) rats.
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