Large-scale commercial-grade volatile fatty acids production from sewage sludge and food waste: A holistic environmental assessment.

The valorization of sewage sludge and food waste to produce energy and fertilizers is a well-stablished strategy within the circular economy. Despite the success of numerous laboratory-scale experiments in converting waste into high-value products such as volatile fatty acids (VFAs), large-scale implementation remains limited due to various technical and environmental challenges. Here, we evaluate the environmental performance of a hypothetical large-scale VFAs biorefinery located in Galicia, Spain, which integrates fermentation and purification processes to obtain commercial-grade VFAs based on primary data from pilot plant operations.

Methodological guide and roadmap to assess the compliance of wastewater treatment plants with sustainability and circularity criteria.

Environmental certification has come up as a voluntary action to demonstrate a minimum quality level when it comes to the introduction of ecological-friendly principles in decision-making. However, most of the work done so far has focused on the food and agroforestry sectors and on the production and processing stages of the value chain rather than end-of life strategies. The present study aims to provide a roadmap that facilitates the evaluation of the performance wastewater facilities from sustainable and circularity perspectives.

Duration of cryostorage is not associated with rates of thaw survival, fertilization, blastulation and ploidy, or pregnancy outcomes of vitrified human oocytes.

Purpose: This study is to evaluate duration of oocyte cryostorage and association with thaw survival, fertilization, blastulation, ploidy rates, and pregnancy outcomes in patients seeking fertility preservation.

Methods: Retrospective cohort study to evaluate clinical outcomes in patients who underwent fertility preservation from 2011 to 2023 via oocyte vitrification for non-oncologic indications. Primary outcome was thaw survival rate.

Tivozanib Monotherapy in the Frontline Setting for Patients with Metastatic Renal Cell Carcinoma and Favorable Prognosis.

Purpose Of Review: In this review, we discuss which patients with metastatic clear cell renal cell carcinoma (mRCC) may be most suitable for frontline tyrosine kinase inhibitor (TKI) monotherapy, a treatment option supported by emerging long-term efficacy data including overall survival and quality of life. We specifically focus on tivozanib, a potent and selective inhibitor of vascular endothelial growth factor receptor, which has comparable efficacy to other single-agent TKIs in frontline treatment for mRCC while exhibiting fewer off-target side effects.

Recent Findings: Combination therapy with TKIs and checkpoint inhibitors (CPIs) and CPI/CPI combination therapies, as well as TKI monotherapy are recommended frontline treatment options for mRCC.

An Analysis of Fertility Preservation Offerings for Transgender Youth on United States Pediatric Hospital Websites.

Purpose: To survey United States (U.S.) pediatric hospital websites for information about fertility preservation (FP) for transgender patients.