Publications by authors named "S Espinosa"
Aims: Patients with D-transposition of the great arteries (D-TGA) and atrial switch experience late morbidity and mortality related to atrial arrhythmias and systemic right ventricular (SRV) failure. We sought to analyze the influence of atrial arrhythmias on long-term outcomes in this group.
Methods: A retrospective review of all patients with D-TGA and atrial switch followed at a tertiary care center was performed.
Formamide (NHC(O)H) has been observed both in the interstellar medium (ISM), being identified as a potential precursor of prebiotic molecules in space, and in the Earth's atmosphere. In these environments where temperature is very distinct, hydroxyl (OH) radicals may play an important role in the degradation of NHC(O)H. Thus, in this work, we report for the first time the experimental study of the temperature dependence of the gas-phase removal of OH in the presence of NHC(O)H over the 11.
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- Changes in lunar illumination affect the risks and opportunities for animals, influencing their behavior and interactions, particularly in tropical forests.
- The study analyzed long-term data from 86 mammal species across 17 protected forests, revealing that many species avoid moonlight during full moons (lunar phobia) more than they are attracted to it (lunar philia).
- The findings highlight that lunar phases significantly influence mammal activity even in dense forests, which may be more pronounced in areas that are degraded or fragmented.
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- Management decisions in wildlife conservation should consider both habitat selection and demographic performance, as habitat selection alone may not reflect true species viability.
- This study focuses on the greater sage-grouse to illustrate how mapping habitat selection against survival rates can reveal important mismatches and trade-offs throughout different reproductive life stages.
- By integrating demographic measures into habitat management, conservation efforts can be more effectively tailored to enhance species survival and resource allocation, particularly during critical life stages.
The aim of this work was to obtain and evaluate, as antiprotozoals, new derivatives of benzoate imidazo-1,3,4-thiadiazole - based on the concepts of molecular repositioning and hybridization. In the design of these compounds, two important pharmacophoric subunits of the fexnidazole prototype were used: metronidazole was used as a repositioning molecule, p-aminobenzoic acid was incorporated as a bridge group, and 1,3,4-thiadiazole group was incorporated as a second pharmacophore, which at position 5 has an aromatic group with different substituents incorporated. The final six compounds were obtained through a five-step linear route with moderate to good yields.
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