Publications by authors named "S Espino-Y-Sosa"

Pregnancy increases the demand for essential metal ions to support fetal development, making the maternal metal ion status a critical determinant of perinatal outcomes. This prospective cohort study examined changes in metal ion levels across the three trimesters, evaluated the influence of preexisting metabolic conditions on the metal ion status, and assessed the associations between maternal metal ion levels and perinatal outcomes in 206 pregnant women from the Biochemical and Epigenetic Origin of Overweight and Obesity (OBESO) cohort receiving care at the Instituto Nacional de Perinatología in Mexico City from 2017 to 2020. Six essential metal ions (iron, zinc, copper, calcium, magnesium, and phosphorus) were measured in blood samples using inductively coupled plasma optic emission spectrometry.

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Gestational diabetes (GD) is a metabolic disorder characterized by glucose intolerance during pregnancy, significantly impacting maternal and fetal health. Its global prevalence is approximately 14%, with risk factors including obesity, family history of diabetes, advanced maternal age, and ethnicity, which are linked to cellular and molecular disruptions in glucose regulation and insulin resistance. GD is associated with short- and long-term complications for both the mother and the newborn.

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Background: Laparoscopic cholecystectomy is known for its minimally invasive nature, but postoperative pain management remains challenging. Despite the enhanced recovery after surgery (ERAS) protocol, regional analgesic techniques like modified perichondral approach to thoracoabdominal nerve block (M-TAPA) show promise. Our retrospective study evaluates M-TAPA's efficacy in postoperative pain control for laparoscopic cholecystectomy in a middle-income country.

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Article Synopsis
  • - Preeclampsia (PE) is a complex pregnancy disorder characterized by high blood pressure and protein in urine, posing risks to mothers and their babies; its underlying mechanisms involve abnormal placentation and systemic responses.
  • - The condition is driven by inadequate placental development, leading to hypoxia and the release of anti-angiogenic factors, which cause endothelial dysfunction and increased inflammation; genetic factors also play a crucial role.
  • - Despite some promising therapeutic strategies targeting oxidative stress and inflammation, effective prevention and treatments for PE are still lacking, emphasizing the need for ongoing research in understanding and managing the disorder.
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Aim: Gestational diabetes (GD) is a global health concern with significant implications for maternal and neonatal outcomes. This study investigates the association between early GD (eGD) diagnosis (<24 weeks), pharmacotherapy requirements and adverse neonatal outcomes.

Materials And Methods: A cohort of 369 pregnant women underwent a 75-g oral glucose tolerance test.

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