Publications by authors named "S Ennas"

Article Synopsis
  • - Henoch-Schonlein purpura (HSP), an IgA-mediated small-vessel vasculitis, can occur after respiratory infections, vaccinations, or malignancies, with recent cases linked to SARS-CoV2 infection and vaccination during the COVID-19 pandemic.
  • - A systematic review identified 38 reports detailing 44 patients with de-novo HSP following SARS-CoV2 vaccination; symptoms included palpable purpura and various complications like joint pain, abdominal issues, and renal involvement.
  • - Findings suggest that the immune response from COVID-19 vaccination or infection may trigger HSP, marked by elevated inflammation markers and notable IgA involvement, indicating a potential link between the immune response and HSP development.
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Short bowel syndrome (SBS) with intestinal failure (IF) is a rare but severe complication of Crohn's disease (CD), which is the most frequent benign condition that leads to SBS after repeated surgical resections, even in the era of biologics and small molecules. Glucagon-like peptide-2 analogues have been deeply studied recently for the treatment of SBS-IF. These drugs have a significant intestinotrophic effect and the potential to reduce the chronic dependence of SBS-IF patients on parenteral support or nutrition.

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Backgrounds And Objective: Aim of the present study was to evaluate the clinical correlates of small bowel CT patterns in patients with Crohn's disease (CD), as compared to barium studies and endoscopic findings, as far as parameters of disease activity are concerned.

Material And Methods: Thirty five patients with pathologically proven CD were studied by means of helical single detector CT (13) or multidetector CT (22), after administration of low density contrast by mouth (13) or by nasojeunal tube (22). Eight hours later, all patients were studied with barium administered by mouth (13) or with barium and methilcellulose administered by nasojeunal tube (22).

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