Design, Synthesis, Characterization, and Molluscicidal Activity Screening of New Nicotinonitrile Derivatives against Land Snails, .

A new series of nicotinonitrile derivatives - was designed and synthesized from the starting material ()-3-(4-chlorophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one () to assess their molluscicidal activity. The newly synthesized nicotinonitrile compounds - were characterized based on FTIR, H-NMR, and C-APT NMR spectra as well as elemental microanalyses. The target compounds - were screened for their toxicity effect against land snails and were compared to Acetamiprid as a reference compound.

A clinical comparison of Dacron patch closure of small-caliber carotids compared with primary closure of large-caliber carotids after endarterectomy.

The objective was to study results of carotid endarterectomies performed between 1975 and 1991, comparing primary closure to Dacron patch closure. This was a retrospective study. Data from patient follow-up by physical examination, chart review, and Duplex study were used.

Carotid endarterectomy with primary closure does not adversely affect the rate of recurrent stenosis.

Objectives: To review our results with carotid endarterectomy using primary closure and to study the incidence of true recurrence in this group of patients. A secondary objective was to review the effect of risk factors on recurrence of stenosis following carotid endarterectomy.

Design: Cohort study.

Femoropopliteal bypass with externally supported knitted Dacron grafts: a follow-up of 200 grafts for one to twelve years.

Purpose: This article reports our experience with externally supported, preclotted knitted Dacron grafts in femoropopliteal bypass.

Methods: This is a retrospective analysis of a consecutive series of 154 patients who received 200 grafts (175 above knee and 25 below knee). Follow-up extended to 12 years (mean 59 1/2 months).

Platelet aggregometry can accurately predict failure of externally supported knitted Dacron femoropopliteal bypass grafts.

Purpose: Our purpose was to evaluate whether a method for quantification of platelet aggregability will predict failure of knitted Dacron femoropopliteal bypass grafts.

Methods: A numerically derived platelet aggregation (PA) score, based on the aggregation pattern and platelet count, was determined in the 40 patients available for platelet analysis who underwent 53 femoropopliteal bypass grafts with preclotted, 6 mm, externally supported knitted Dacron grafts from 1981 to 1991 (mean follow-up 50 months). The preoperative score was found to remain stable after surgery, enabling the use of postoperative values when preoperative values were not available.