A recent immunological concept of some nasal diseases.

In this study, we have attempted to summarize and clarify the concept of nasal permeability to antigens such as inhaled particles, bacterial breakdown products and medicaments. The mature epithelium retains the capacity to allow macromolecules to penetrate by a pinocytotic mechanism, which is more pronounced during the neonatal period. The vast majority of individuals have no ill effects from the nasal transport of large molecules.