Publications by authors named "S Eisenschenk"

Article Synopsis
  • EEG is crucial for diagnosing and managing neurologic issues like seizures and brain injuries in veterans, prompting a study on the infrastructure of EEG services within the Veterans Administration (VA).
  • A survey sent to 123 VA hospitals revealed that while most had EEG services, only a minority offered continuous EEG, and many facilities reported a lack of adequate resources such as EEG technologists and machines.
  • The study indicates significant variability in EEG infrastructure and highlights that expanding tele-EEG services could improve access and patient management in resource-limited environments.
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Article Synopsis
  • Patients experiencing post-anoxic status epilepticus (PASE) after cardiac arrest face poor outcomes due to a combination of therapeutic nihilism and the difficulty in managing their seizures, which creates a bleak outlook.
  • This negative cycle is exacerbated by the exclusion of hypoxic-ischemic causes from clinical trials, limiting the development of effective treatments for these patients.
  • Early treatment with vigabatrin, which inhibits the breakdown of GABA, shows promise as it may enhance the effectiveness of other GABA-targeting medications in managing PASE.
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Tiagabine has been associated with reports of status epilepticus as well as encephalopathy, even when used within therapeutic doses. Vagus nerve stimulation (VNS) has been used successfully to reduce seizure frequency in the outpatient setting as well as in the acute setting of status epilepticus. It is also theorized to reduce cortical synchronization.

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Sleep-disordered breathing (SDB) can be a sequela of stroke caused by vascular injury to vital respiratory centers, cerebral edema, and increased intracranial pressure of space-occupying lesions. Likewise, obstructive sleep apnea (OSA) contributes to increased stroke risk through local mechanisms such as impaired ischemic cerebrovascular response and systemic effects such as promoting atherosclerosis, hypercoagulability, cardiac arrhythmias, vascular-endothelial dysfunction, and metabolic syndrome. The impact of OSA on stroke outcomes has been established, yet it receives less attention in national guidelines on stroke management than hyperglycemia and blood pressure dysregulation.

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Background: Levetiracetam is commonly used as a prophylactic antiseizure medication in patients undergoing surgical resection of brain tumors.

Objective: To quantitate side effects experienced in patients treated with 1 week vs 6 weeks of prophylactic levetiracetam using validated measures for neurotoxicity and depression.

Methods: Patients undergoing surgical resection of a supratentorial tumor with no seizure history were randomized within 48 hours of surgery to receive prophylactic levetiracetam for the duration of either 1 or 6 weeks.

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