Publications by authors named "S E de Laszlo"

Introduction: Intestinal ischemia/reperfusion (I/R) injury is associated with high mortality and there is an unmet need for novel therapies. The intestinal expression of cyclooxygenase-2 (COX-2) increases rapidly after mesenteric I/R, but it is still a question of debate whether selective COX-2 inhibitors can mitigate I/R-induced gut injury. Here we aimed to compare the effect of celecoxib and rofecoxib, two selective COX-2 inhibitors, on intestinal I/R-induced injury in rats.

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Kettlebell as a sport has gained recognition worldwide. We characterized the physiological responses induced by a simulated kettlebell competition routine in experienced kettlebell athletes (n = 26) in a two-group, pre-post plus short-term follow-up, non-randomized experiment. The experimental group (EXP) included 13 kettlebell athletes, while the control group (CON) consisted of 13 individuals with prior recreational exposure to kettlebell activities.

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Article Synopsis
  • The study presents a new optochemical screening method for detecting zinc (Zn) and lead (Pb) in various solutions, addressing the need for effective analysis due to their biological and environmental significance.
  • A three-step microplate modification technique was developed, which involves plasma treatment, linker-docking, and photocatalytic copolymerization, enhancing the sensitivity and functionality of the microplate for sensing.
  • This innovative tool can analyze over 1000 samples per hour and operates effectively with standard microplate readers, requiring only a minimal sample volume while achieving detection limits of 8.0 × 10 and 3.0 × 10 mol/L for Zn and Pb, respectively.
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Background: Operative treatment is widely used for acute proximal hamstring avulsions, but its effectiveness compared with that of nonoperative treatment has not been shown in randomized trials.

Methods: In this noninferiority trial at 10 centers in Sweden and Norway, we enrolled patients 30 to 70 years of age with a proximal hamstring avulsion in a randomized trial and a parallel observational cohort. Treatments were operative reinsertion of the tendons or nonoperative management.

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Article Synopsis
  • - Persistent trigeminal artery disease is a common type of persistent carotid-vertebrobasilar anastomosis, often found unilaterally and detected through imaging methods like MRA and angioCT.
  • - While it can cause symptoms such as headaches or nerve palsies, it frequently remains asymptomatic and is discovered incidentally.
  • - A case is presented involving a young woman who found out she had this malformation during an MRA after suffering from persistent headaches that did not improve with treatment.
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