Publications by authors named "S E Trabucco"

Article Synopsis
  • A study at a community hospital in Southern Italy examined how androgen deprivation therapy (ADT) affects the quality of life in men with prostate cancer over six months.
  • The findings showed significant declines in physical functioning, increasing fatigue, insomnia, and sexual function, with many participants also reporting feelings of depression and negative body image.
  • The results highlight the need for holistic care that addresses both the physical and emotional challenges faced by these patients during treatment.
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Background: Genomic fusions are potent oncogenic drivers across cancer types and many are targetable. We demonstrate the clinical performance of DNA-based comprehensive genomic profiling (CGP) for detecting targetable fusions.

Materials And Methods: We analyzed targetable fusion genes in >450 000 tissue specimens profiled using DNA CGP (FoundationOne CDx, FoundationOne).

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Glitches, spin-up events in neutron stars, are of prime interest, as they reveal properties of nuclear matter at subnuclear densities. We numerically investigate the glitch mechanism due to vortex unpinning using analogies between neutron stars and dipolar supersolids. We explore the vortex and crystal dynamics during a glitch and its dependence on the supersolid quality, providing a tool to study glitches from different radial depths of a neutron star.

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Prostate cancer is one of the most common tumors among the male population. Magnetic resonance imaging (MRI), standardized by the PI-RADS version 2.1 scoring system, has a fundamental role in detecting prostate cancer and evaluating its aggressiveness.

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