Publications by authors named "S E Schwartz"
Article Synopsis
- The primary motor cortex (M1) is essential for learning motor skills, and dopaminergic signaling from the ventral-tegmental area (VTA) plays a significant role in this process.
- Using techniques like calcium imaging and chemogenetic inhibition, researchers found that learning a dexterity task leads to a reorganization of M1 layer 2-3, changing how neurons connect and communicate while maintaining overall activity levels.
- Blocking VTA signals during learning halted these neural changes, highlighting the importance of dopaminergic input in developing outcome signaling and refined connectivity in M1, which is crucial for acquiring new motor skills.
Pancreatic ductal adenocarcinoma (PDAC) is a very challenging disease with a very poor prognosis. It is characterized by a dense desmoplastic stroma that hampers drug penetration and limits the effectiveness of conventional chemotherapy (CT). As an alternative, the combination of CT with hyperthermia (HT) has been proposed as an innovative treatment modality for PDAC.
View Article and Find Full Text PDFClimate-related disasters pose significant risks to mental health and well-being globally. Individuals from disaster-prone regions, such as Puerto Rico, are at even greater risk. The devastating effects of recurrent hurricanes, compounded with pre-existing structural disparities (e.
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