Publications by authors named "S E Salomonsson"

Importance: A diagnosis of bacterial meningitis in childhood can lead to permanent neurological disabilities. Few studies have examined long-term consequences for work ability in adulthood.

Objective: To compare earnings, work loss, and educational attainment between adults diagnosed with bacterial meningitis in childhood and population comparators.

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Article Synopsis
  • The study evaluates the reliability and validity of two common self-reported measures for somatic symptoms: the Patient Health Questionnaire-15 (PHQ-15) and the Somatic Symptom Scale-8 (SSS-8).
  • Extensive data was extracted from 305 studies involving over 361,000 participants, focusing primarily on routine care and the general population.
  • Results indicated that both scales measure specific symptom domains and overall symptom burden, with the PHQ-15 showing good reliability (α = 0.81) while certain items had low correlations, and the SSS-8 also showing strong reliability (α = 0.80).
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Background: Lower respiratory tract infections (LRTIs) are a major global health concern, particularly among older adults, who have an increased risk of poorer health outcomes that persist beyond the acute infectious episode. We aimed to investigate the mid-term (up to 7 years) and long-term (up to 12 years) effects of LRTIs on the objective health status trajectories of older adults, while also considering potential sex differences.

Methods: Cohort data of adults aged ≥ 60 years from the Swedish National study of Aging and Care in Kungsholmen (SNAC-K) collected between 2001 and 2016 was analyzed.

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Article Synopsis
  • Access to evidence-based therapy for PTSD is limited, and a new approach called blended Trauma-focused Cognitive Therapy (bTF-CT) combines online modules with some in-person sessions to improve accessibility while preserving the benefits of traditional therapy.* -
  • The study evaluated the feasibility and effectiveness of bTF-CT by providing it to 17 participants in various clinics, using questionnaires and the PTSD Symptom Checklist (PCL-5) to measure outcomes like treatment satisfaction and symptom changes.* -
  • Results showed high satisfaction and retention rates, with most participants experiencing significant reductions in PTSD symptoms, suggesting that bTF-CT is a viable treatment option that merits further large-scale testing against standard therapies.*
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Expansion of intronic GGGGCC repeats in the gene causes amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Transcription of the expanded repeats results in the formation of RNA-containing nuclear foci and altered RNA metabolism. In addition, repeat-associated non-AUG (RAN) translation of the expanded GGGGCC-repeat sequence results in the production of highly toxic dipeptide-repeat (DPR) proteins.

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