Assessing the Role of Dark Sweet Cherry ( L.) Consumption on Cognitive Function, Neuropeptides, and Circadian Rhythm in Obesity: Results from a Randomized Controlled Trial.

Obesity is linked to a higher risk of cognitive impairment. The objective of this single blind randomized trial was to evaluate the impact of dark sweet cherry (DSC) intake on cognitive function in obese adults. Participants (body mass index (BMI): 30-40 kg/m, >18 years, without chronic diseases and/or antibiotic use) consumed 200 mL of DSC drink with 3 g of cherry powder ( = 19) or an isocaloric placebo drink ( = 21) twice daily for 30 days.

MCF7 breast cancer anabolic capacity reduced with CRISPR/Cas9-mediated stable overexpression of DEPTOR.

The hyperactivation of mTOR is a significant contributor to the development and progression of a number of human diseases, including a majority of human cancers. Although there have been many scientific and clinical efforts to reduce the impact of mTOR hyperactivation on downstream cellular metabolism, we aimed to mitigate this hyperactivation through a novel targeted gene edit of the intrinsic mTOR inhibitor, DEP domain containing MTOR interacting protein (DEPTOR), in MCF7 human breast cancer cells. Using publicly available bioinformatics tools, we demonstrate that DEPTOR gene expression is low in breast cancers compared with healthy tissues and that DEPTOR expression predicts overall survival, recurrence-free survival, and distant metastasis-free survival in breast cancer patients.

The Effect of Choline and Resistance Training on Strength and Lean Mass in Older Adults.

Choline plays many important roles, including the synthesis of acetylcholine, and may affect muscle responses to exercise. We previously observed correlations between low choline intake and reduced gains in strength and lean mass following a 12-week resistance exercise training (RET) program for older adults. To further explore these findings, we conducted a randomized controlled trial.

The impact of nutrition on visual cognitive performance in the nutrition, vision, and cognition in sport study.

Introduction: The purpose of this study was to examine the influence of nutritional intake on visual perceptual-cognitive performance (VCP) in young healthy adults.

Methods: Ninety-eight healthy men ( = 38) and women ( = 60) aged 18-33 years participated and maintained their usual dietary intake throughout the study. VCP was measured using the NeuroTracker CORE (NT) 3-Dimensional (3-D) software program (15 training sessions) over a 15-day period.

Nutrition, lifestyle, and cognitive performance in esport athletes.

Introduction: Electronic sports, termed esports, is a growing athletic activity in which high levels of attention and cognitive performance are required. With its increasing popularity and competitiveness, interest in strategies to improve performance have emerged. Improving esports athlete performance, namely cognitive endurance, and resilience, may lie in nutritional or lifestyle factors.