Aim: Acute myocarditis (AM) is increasingly diagnosed in the era of more sensitive imaging techniques. The natural history of AM diagnosed on cardiac magnetic resonance imaging (cMRI) may be different to historic cohorts due to the detection of milder disease. This study aims to measure the outcome of patients with AM detected by cMRI.
View Article and Find Full Text PDFBackground: Acute respiratory distress syndrome (ARDS) is highly heterogeneous, both in its clinical presentation and in the patient's physiological responses to changes in mechanical ventilator settings, such as PEEP. This study investigates the clinical efficacy of a physiological model-based ventilatory decision support system (DSS) to personalize ventilator therapy in ARDS patients.
Methods: This international, multicenter, randomized, open-label study enrolled patients with ARDS during the COVID-19 pandemic.
This study investigated the clinical and physiological response to use of the BEACON Caresystem, a bedside open-loop decision support system providing advice to guide clinicians when weaning patients from invasive mechanical ventilation. Multicenter prospective study conducted in five adult intensive care units in the UK. Following screening and assent, intubated patients mechanically ventilated for > 24 h were randomized to intervention or usual care.
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