CD36 receptor regulates malaria-induced immune responses primarily at early blood stage infection contributing to parasitemia control and resistance to mortality.

In malaria, CD36 plays several roles, including mediating parasite sequestration to host organs, phagocytic clearance of parasites, and regulation of immunity. Although the functions of CD36 in parasite sequestration and phagocytosis have been clearly defined, less is known about its role in malaria immunity. Here, to understand the function of CD36 in malaria immunity, we studied parasite growth, innate and adaptive immune responses, and host survival in WT and mice infected with a non-lethal strain of Compared with mice, WT mice had lower parasitemias and were resistant to death.

Solitary urethrocutaneous fistula managed by the PATIO repair.

Objective: A novel technique has been described for repairing penile urethrocutaneous fistula: the PATIO ('preserve the tract and turn it inside out') repair. We report our experience with this technique in managing solitary urethrocutaneous fistula following primary hypospadias repair.

Methods: Children with fistulae underwent the PATIO technique of repair.