Associations of sexual orientation and state-level antidiscrimination policy protections with alcohol, tobacco, and mental health outcomes in a U.S. sample of adolescents and adults.

Introduction: Structural stigma has important health implications for sexual minority individuals, including alcohol and tobacco use, and mental health. This study examined associations of structural stigma with alcohol and tobacco use and internalizing symptoms while considering sexual identity changes and multiple dimensions of sexual orientation among adolescents and adults in the U.S.

Heterogeneity in Prescription Opioid Misuse Motives by Age in Adolescents and Young Adults in the United States.

Objective: Adolescent (12-17 years) and young adult (18-25 years) prescription opioid misuse (POM) is linked to poor health outcomes. We investigated how POM motives vary across these ages and the potential links between motives and other substance use, mental health, and sociodemographic characteristics to help guide screening and prevention.

Methods: Pooled 2015-2019 US National Survey on Drug Use and Health data were used, with 137,858 participants.

Are the Effects of Poor Survey Measurement of Sexual Identity on Estimated Associations between Sexual Identity and Health-Related Measures Moderated by the State-Level Policy Environment?

Including a "something else" response option for survey questions about sexual identity significantly moderates estimated differences between sexual identity subgroups in terms of behaviors and attitudes reported in U.S. health surveys.

ZIP8 Is Upregulated in the Testis of Mice.

Background/objectives: Manganese is an essential nutrient involved in various biological processes, including reproductive health, yet the mechanisms regulating its homeostasis in the testis remain poorly understood.

Methods And Results: In this study, we investigated the expression and regulation of key manganese transporters-ZIP8, ZIP14, and ZnT10-in mouse testes. Immunoblotting analyses revealed that ZIP8 is expressed in the testes, while ZIP14 and ZnT10 were undetectable.