Publications by authors named "S E Lock"
Article Synopsis
- This scoping review focused on physical activity and sedentary behavior interventions for individuals with frailty and multiple long-term conditions (MLTCs), including their caregivers.
- Researchers examined ten databases from 2000 to October 2023, ultimately retaining 155 papers from 144 studies, most of which were randomized controlled trials with participants averaging 73 years old.
- The findings highlighted that most interventions centered on structured exercise, had a high adherence rate, and yielded positive outcomes, but emphasized the need for more research on habitual activity, caregiver involvement, and a deeper understanding of individual characteristics like MLTCs and ethnicity.
A Sister Mary Joseph's nodule (SMJN) is characterized by a palpable umbilical nodule and is often a clinical indicator of the metastasis of an advanced abdominal or pelvic malignancy. Observing the cutaneous manifestation of an abdomino-pelvic malignancy is a relatively rare phenomenon due to the appearance of visible changes in the later stages of the disease. With the pancreas being a less common primary tumor site for SMJN, this case report describes a 57-year-old male diagnosed with metastatic pancreatic adenocarcinoma with a SMJN.
View Article and Find Full Text PDFBackground And Purpose: Disregarding the increase of relative biological effectiveness (RBE) may raise the risk of acute and late adverse events after proton beam therapy (PBT). This study aims to explore the relationship between variable RBE (above 1.1)-induced normal tissue complication probabilities (NTCP) and patient-specific factors, identify patients at high risk of RBE-induced NTCP increase, and assess risk mitigation by incorporating RBE variability into treatment planning.
View Article and Find Full Text PDFRationale And Objectives: To investigate factors influencing the success and complication rate of percutaneous transhepatic biliary drainage (PTBD).
Materials And Methods: PTBD procedures between 2017 and 2022 were enrolled retrospectively. Success rate, complications, and technical considerations were compared using Mann-Whitney U-, X-, and Fishers exact tests.