Publications by authors named "S E Kolb"
The impact of combined heat and drought stress was investigated in and compared to individual stresses to reveal additive effects and interactions. A combination of plant metabolomics and root and rhizosphere bacterial metabarcoding were used to unravel effects at the plant holobiont level. Hierarchical cluster analysis of metabolomics signatures pointed out two main clusters, one including heat and combined heat and drought, and the second cluster that included the control and drought treatments.
View Article and Find Full Text PDFAn established concept to create radical intermediates is photoexcitation of a catalyst to a higher energy intermediate, subsequently leading to a photoinduced electron transfer (PET) with a reaction partner. The known concept of consecutive photoinduced electron transfer (con-PET) leads to catalytically active species even higher in energy by the uptake of two photons. Generally speaking, increased photon uptake leads to a more potent reductant.
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- Today's operating rooms are increasingly complex due to the integration of multiple information sources and applications.
- Although manufacturers are making progress, achieving fully integrated operating rooms is still a work in progress.
- Emerging projects show promise, but they currently lack a scalable networking infrastructure, which could be addressed by advancements anticipated with the upcoming 6G standard.
Article Synopsis
- - CRISPR-engineered CAR T cells show promise in cancer treatments but have been linked to chromosomal issues due to the CRISPR process.
- - The study reveals that increased T cell activation and faster proliferation lead to larger DNA deletions, while non-activated T cells have a lower risk but are less effective for gene editing.
- - A small molecule called pifithrin-α can reduce chromosomal damage while preserving the functionality of CRISPR-engineered T cells, making it a viable strategy for improving genomic safety.