Publications by authors named "S E Jackson"
We assessed the analytical performance of metagenomic workflows using NIST Reference Material (RM) 8376 DNA from bacterial pathogens spiked into two simulated clinical samples: cerebrospinal fluid (CSF) and stool. Sequencing and taxonomic classification were used to generate signals for each sample and taxa of interest and to estimate the limit of detection (LOD), the linearity of response, and linear dynamic range. We found that the LODs for taxa spiked into CSF ranged from approximately 100 to 300 copy/mL, with a linearity of 0.
View Article and Find Full Text PDFSortases are critical cysteine transpeptidases that facilitate the attachment of proteins to the cell wall in Gram-positive bacteria. These enzymes are potential targets for novel antibiotic development, and versatile tools in protein engineering applications. There are six classes of sortases recognized, yet class A sortases (SrtA) are the most widely studied and utilized.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the relationship between vaping and smoking in young people, aiming to improve e-cigarette policy by addressing gaps in current research.
- Recommendations were developed from a critical review of existing studies and stakeholder input, resulting in a final set of 23 guidelines for future research.
- Key recommendations include considering socio-economic and contextual factors in vaping-smoking associations and ensuring representative data from diverse countries, alongside specific reporting on e-cigarette characteristics.