Publications by authors named "S E Gradinaru"

Introduction: Colorectal cancer (CRC) is one of the most common cancers occurring globally. Surgery for CRC often extends hospital stays due to complications, as patients must meet nutritional needs and regain mobility before discharge. Longer hospital stays, required for extended monitoring and care, can increase the risk of further complications, creating a cycle where extended stays lead to more issues.

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Article Synopsis
  • A 26-year-old male with severe spinal tuberculosis faced worsening back pain for five years, initially managed with over-the-counter medication but refused surgery, leading to significant disease advancement.
  • Imaging in 2022 confirmed tuberculosis after a biopsy, showing extensive infection and large abscesses, despite a year of anti-tuberculous therapy.
  • The patient underwent a successful two-stage surgical intervention, resulting in pain relief and no neurological issues, emphasizing the need for timely diagnosis and comprehensive treatment in severe cases.
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: Systemic inflammatory indices have been largely investigated for their potential predictive value in multiple inflammatory, infectious, and oncological diseases; however, their value in colorectal cancer is still a subject of research. This study investigates the dynamics of pre- and postoperative values of NLR, PLR, SII, and MLR in patients with colorectal cancer and their predictive value for early postoperative outcomes. : A 2-year retrospective cohort study was performed on 200 patients operated for colorectal adenocarcinoma.

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Enhanced Recovery After Surgery (ERAS) represents evidence-based transformation in perioperative care, which has been demonstrated to reduce both recovery times and postoperative complication rates. The aim of the present study was to evaluate the clinical significance of the ERAS program in comparison with conventional postoperative care. This longitudinal cohort observational study enrolled 120 consecutive patients diagnosed with intestinal obstruction caused by colorectal cancers, with 40 patients in the ERAS group and 80 patients receiving conventional postoperative care forming the non-ERAS group.

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Pancreatic heterotopy is a rare entity defined as the presence of abnormally located pancreatic tissue without any anatomical or vascular connection to the normal pancreas. Heterotopic pancreatic tissue can be found in various regions of the digestive system, such as the stomach, duodenum, and upper jejunum, with the less commonly reported location being the gallbladder. Gallbladder pancreatic heterotopia can be either an incidental finding or diagnosed in association with cholecystitis.

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