How Does Diploic Space Thickness Change With Age?

Background: Cranial defects from trauma, surgery, or congenital conditions require precise reconstruction to restore cranial vault integrity. Autogenous calvarial grafts are preferred for their histocompatibility and biomechanical properties, but their success depends on a well-developed diploic space. Although prior studies have described overall skull thickness development, less is known about how diploic thickness changes through adulthood.

Content analysis of perceptions of combined pharmacobehavioral treatment for American Indian people with opioid use disorder.

Objective: Both opioid misuse and overdose mortality have disproportionately impacted the American Indian population. Although medications for opioid use disorder, such as buprenorphine (BUP-NX), are highly effective in reducing overdose mortality, questions have been raised about the cultural acceptability of Western medical approaches in this population. Understanding patients' desired recovery pathways can lead to more culturally appropriate, patient-centered, and effective approaches to opioid use disorder (OUD) treatment.

A cooperative model for metallocene catalyst activation by methylaluminoxane.

Activation of rac-MeSi(η-Ind)ZrMe (SBIZrMe) and sheet models for MAO, (MeAlO)(MeAl) (6,4), (MeAlO)(MeAl) (7,5), and (MeAlO)(MeAl) (26,9) was studied DFT. These activators can reversibly form an outer-sphere ion-pair (OSIP) [SBIZrMeAlMe] [(MeAlO)(MeAl)Me] 3 ([,] = [7,4]and [26,8]) or a contact ion-pair (CIP) SBIZrMe-μ-Me-6,4 (2b) from SBIZrMe. Dissociation of MeAl from 3 to form CIP SBIZrMe-μ-Me-, (2) is generally unfavourable but reversible in toluene continuum.

Exploring the Crystal Landscape of Mandelamide and Chiral Resolution via Cocrystallization.

The crystal structures of (±)-mandelamide, -mandelamide, and enantioenriched mandelamide (94 : 6 ) were determined. Diastereomeric cocrystal pairs of -mandelamide with both enantiomers of mandelic acid and proline were synthesized. The diastereomeric cocrystal pairs of -mandelamide with /-mandelic acid form 1:1 cocrystals in each case, while the diastereomeric cocrystal pairs of -mandelamide with proline have different stoichiometries.

Education Research: Rewarding Our Educators: Design and Evaluation of a Program to Fund Teaching in Neurology.

Background And Objectives: Pressures on academic physician educators to generate clinical revenue or research grants may threaten faculty engagement as teachers. Neurology has historically prized its outstanding educators, but programs that provide financial support for teaching are lacking. We developed an opt-in, financial, teaching incentive program in an academic neurology department and evaluated its impact on faculty experience, motivation, and identity.