Policy interventions and technological advances are mitigating emissions of air pollutants from motor vehicles. As a result, vehicle fleets are expected to progressively combust fuel more efficiently, with a declining ratio of carbon monoxide to carbon dioxide (CO/CO) in their emissions. We assess trends in traffic combustion efficiency in Los Angeles (LA) and Salt Lake City (SLC) by measuring changes in summertime on-road CO/CO between 2013 and 2021 using mobile observations.
View Article and Find Full Text PDFGenomics Proteomics Bioinformatics
December 2024
High-fidelity (HiFi) sequencing has facilitated the assembly and analysis of the most repetitive region of the genome, the centromere. Nevertheless, our current understanding of human centromeres is based on a relatively small number of telomere-to-telomere assemblies, which have not yet captured its full diversity. In this study, we investigated the genomic diversity of human centromere higher order repeats (HORs) via both HiFi reads and haplotype-resolved assemblies from hundreds of samples drawn from ongoing pangenome-sequencing projects and reprocessed them via a novel HOR annotation pipeline, HiCAT-human.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
October 2024
Increasing heatwaves are threatening forest ecosystems globally. Leaf thermal regulation and tolerance are important for plant survival during heatwaves, though the interaction between these processes and water availability is unclear. Genotypes of the widely distributed foundation tree species were studied in a controlled common garden during a record summer heatwave-where air temperature exceeded 48 °C.
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