Characterizing sexuality and assessing predictors of sexual satisfaction in patients with multiple myeloma and other hematological cancers.

Purpose: Existing studies documenting cancer-related sexual concerns among hematological cancer patients tend to group all types of hematological cancer together, overlooking potentially unique concerns associated with multiple myeloma (MM). This study is the first to characterize sexuality in MM and to examine predictors of sexual satisfaction for MM, comparatively with participants with other hematological cancer types.

Methods: We conducted a cross-sectional self-report survey-based study.

Ultraprecise Determination of Cs(nS_{1/2}) and Cs(nD_{J}) Quantum Defects for Sensing and Computing: Evaluation of Core Contributions.

We make absolute frequency measurements of Cs Rydberg transitions, |6S_{1/2},F=3⟩→|nS_{1/2}(n=23-90)⟩ and |nD_{3/2,5/2}(n=21-90)⟩, with an accuracy of less than 72 kHz. The quantum defect parameters for the measured Rydberg series are the most precise obtained to date. The quantum defect series is terminated at δ_{4}, showing that prior fits requiring higher order quantum defects reflect uncertainties in the observations.

Similarities and distinctions in the activation of the Pdr1 regulatory pathway by azole and non-azole drugs.

Unlabelled: Incidences of fluconazole (FLC) resistance among clinical isolates are a growing issue in clinics. The pleiotropic drug response network in confers azole resistance and is defined primarily by the ZnCys zinc cluster-containing transcription factor Pdr1 and target genes such as , which encodes an ATP-binding cassette transporter protein thought to act as an FLC efflux pump. Mutations in the gene that render the transcription factor hyperactive are the most common cause of fluconazole resistance among clinical isolates.

Similarities and distinctions in the activation of the Pdr1 regulatory pathway by azole and non-azole drugs.

Incidences of fluconazole (FLC) resistance among clinical isolates is a growing issue in clinics. The pleiotropic drug response (PDR) network in . confers azole resistance and is defined primarily by the ZnCys zinc cluster-containing transcription factor Pdr1 and target genes such as , that encodes an ATP-binding cassette transporter protein thought to act as a FLC efflux pump.