Publications by authors named "S E Ayyad"
Background And Aim: Globally, COVID-19 has had a profound impact on food and nutrition security. This paper aims to gather the perspective from Transforming India's Green Revolution by Research and Empowerment for Sustainable food Supplies (TIGR2ESS) Flagship Project 6 (FP-6) team on the impact of COVID-19 on the food systems in India. The responses collected will be used for further research projects after TIGR2ESS ends in March 2022.
View Article and Find Full Text PDFComplex diseases involve multifaceted etiological components, which limit the effectiveness of conventional targeted therapies. Therefore, standard medicinal treatments often face significant challenges and failures when addressing these disease conditions. Furthermore, the growing interest in multidrug resistance (MDR), the occurrence of adverse drug reactions related to use traditional approaches, and the limited clinical efficacy of single-target drug therapy have increased the demand for innovative drug treatments.
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- - The study focused on soft coral collected from the Red Sea and successfully isolated a new compound called [(2)-2,3-dihydroxypropyl] (2)-2-hydroxypentadecanoate, along with several other known substances.
- - Researchers used advanced spectroscopic techniques, including 1D and 2D NMR, to determine the chemical structure and composition of the isolated compounds.
- - The newly identified mono-acyl glycerol ester exhibited moderate antimicrobial activity against certain microbial strains and showed weak cytotoxic and antioxidant activities.
Article Synopsis
- Rifaximin is FDA-approved for treating IBS-D but has limited effectiveness due to poor solubility impacting its ability to target E. coli in the mucus layer.
- Adding N-acetylcysteine (NAC) enhances rifaximin's efficacy against E. coli, as shown through tests in both lab assays and a rat model of IBS-D.
- The combination of rifaximin and NAC effectively normalized stool consistency and bacterial levels in the rat model, suggesting potential for improved treatment responses in IBS-D patients.
Article Synopsis
- Hernias that contain organs like the cecum or sigmoid colon are less common than standard inguinal hernias, which usually involve the small intestine and present as swelling in the groin area.
- A 53-year-old man with multiple health issues presented with vomiting and obstruction due to a large incarcerated inguinoscrotal hernia, which required surgery and resulted in complications, including abdominal compartment syndrome.
- Inguinal hernias can lead to serious conditions if not treated, and while they are usually diagnosed through physical exams, the presence of other organs in hernias is rare and often leads to intestinal blockage.