Publications by authors named "S Duquenne"

Article Synopsis
  • * A total of 268 CLE cases were recorded, with a standardized prevalence of 43/100,000 and an estimated incidence of 5.7/100,000 person-years, showing higher rates compared to lighter-skinned populations.
  • * Findings indicate that darker-skinned patients are more likely to experience severe forms of CLE and that certain clinical features may indicate a higher risk of progression to systemic lupus erythematosus (SLE), underscoring the need for tailored patient follow-up.
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Article Synopsis
  • The study aimed to evaluate the prevalence and types of human papillomavirus (HPV) in Reunion Island over a one-year period from 2020 to 2021.
  • The overall HPV prevalence was found to be 14.5%, with the most common HPV types being clusters 56, 59, and 66, along with types 16 and 52; notably, vaccine-covered HPV types were present in over half of the HPV-positive cases.
  • The research concluded that HPV types in the vaccine are most prevalent and linked to severe cervical issues, emphasizing the need to improve vaccination rates on the island to combat cervical cancer effectively.
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Significance: Multilesional basal cell carcinoma (BCC) are spread on sun exposed skin areas, including arms, face and back. The first-line treatment remains the surgical resection or Mohs surgery. Despite its high complexity, Mohs surgery is well practiced in USA and Germany and presents very good results both in esthetic and in carcinology point of view.

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Inhibition of adenosine A2A receptor (A2AR) is a promising approach for cancer immunotherapy currently evaluated in several clinical trials. We here report that anti-obesogenic and anti-inflammatory functions of A2AR, however, significantly restrain hepatocellular carcinoma (HCC) development. Adora2a deletion in mice triggers obesity, non-alcoholic steatohepatitis (NASH), and systemic inflammation, leading to spontaneous HCC and promoting dimethylbenzyl-anthracene (DMBA)- or diethylnitrosamine (DEN)-induced HCC.

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In recent decades, the major scientific advances in oncology have complexified anatomic pathology practice. Collaboration with local and national pathologists is essential for ensuring a high-quality diagnosis. Anatomic pathology is undergoing a digital revolution that implements whole slide imaging in routine pathologic diagnosis.

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