Publications by authors named "S Dubler"
Invasive infections with Aspergillus fumigatus in ICU patients are linked to high morbidity and mortality. Diagnosing invasive pulmonary aspergillosis (IPA) in non-immunosuppressed patients is difficult, as Aspergillus antigen (galactomannan [GM]) may have other causes. This retrospective study analyzed 160 ICU surgical patients with positive GM in broncho-alveolar lavage fluid (BALF), classifying them based on AspICU criteria for suspected IPA (pIPA) or aspiration.
View Article and Find Full Text PDFNeutrophil granulocytes (NGs) are among the key players in the defense against (). To better elucidate a pathophysiological understanding of their role and functions, we applied a human cell model using NGs from healthy participants and septic patients to evaluate their inhibitory effects on the growth of ex vivo. Conidia of (ATCC 204305) were co-incubated with NGs from healthy volunteers or septic patients for 16 h.
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- A study investigated the use of virtual reality (VR) as a non-drug method to reduce pain and anxiety during transcatheter aortic valve replacement (TAVR) procedures in intermediate-risk patients, comparing it to standard care.
- The results showed that patients using VR reported significantly lower anxiety scores and perceived the procedure duration as shorter compared to those who did not use VR, while overall pain levels and procedure times were similar between the two groups.
- The findings support the idea that VR is a safe and effective tool for improving patient comfort during TAVR procedures, highlighting an alternative approach to managing anxiety and pain without sedation.
Background: Critically ill patients, especially those who have undergone solid organ transplantation (SOT), are at risk of invasive pulmonary aspergillosis (IPA). The outcome relevance of adequately treated putative IPA (pIPA) is a matter of debate. The aim of this study is to assess the outcome relevance of pIPA in a cohort of critically ill patients with and without SOT.
View Article and Find Full Text PDFSuperinfections with spp. in patients with Coronavirus disease 2019 (CAPA: COVID-19-associated pulmonary aspergillosis) are increasing. Dexamethasone has shown beneficial effects in critically ill COVID-19 patients.
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