Intubation Versus Tracheotomy Outcomes in Critically Ill COVID-19 Patients in Low-Resource Settings: What Do We Know?

: Patients undergoing prolonged mechanical ventilation commonly require tracheotomy. The main aim of this study was to evaluate the outcomes of tracheotomy for patients with acute respiratory distress syndrome (ARDS) associated with COVID-19 in low-resource settings. : A retrospective, single-center, observational cohort study was performed on patients with ARDS associated with COVID-19.

The Potential Predictive Role of Oxidative Stress and Antioxidant Parameters Regarding Mortality and the Type of Causative Agent in Sepsis.

Oxidative stress represents an imbalance between oxidants and antioxidants, with a predominance of oxidants leading to cellular and tissue damage. Given the limited number of studies showing the predictive value of oxidative stress factors regarding sepsis type, the objectives of this study emerged as follows: to determine whether pro-oxidant and antioxidant values could predictively differentiate between Gram-positive (GP) and Gram-negative (GN) sepsis. Additionally, the study sought to assess whether bacterial type impacts treatment outcomes in sepsis patients.

Do dynamic changes in haematological and biochemical parameters predict mortality in critically ill COVID-19 patients?

Background: Critically ill COVID-19 patients are usually subjected to clinical, laboratory, and radiological diagnostic procedures resulting in numerous findings. Utilizing these findings as indicators for disease progression or outcome prediction is particularly intriguing.

Objectives: Exploring the significance of dynamic changes in haematological and biochemical parameters in predicting the mortality of critically ill COVID-19 patients.

Thrombocytopenia risks in ARDS COVID-19 patients treated with high-dose linezolid during vvECMO therapy: an observational study.

Patients treated with ECMO are at great risk of nosocomial infections, and around 10% of isolates are gram-positive pathogens. Linezolid (LZD) is effective in the treatment of these infections but appropriate dosing is challenging. The aim was to evaluate the occurrence of thrombocytopenia during ECMO when treated with LZD.