Publications by authors named "S Dorado"

Article Synopsis
  • This study analyzed the effectiveness of traditional irrigation methods using a specially designed positive pressure side-vented needle and various suction cannulas for treating mandibles with two root canals.
  • Micro-CT scans enabled detailed computational models to be created, allowing for the assessment of flow patterns, velocities, and pressures during irrigation.
  • Results indicated that using suction cannulas significantly enhanced fluid flow and wall shear stress in the complex root structures, especially in areas that conventional methods struggled to reach.
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Minimal residual disease (MRD) assessment is a known surrogate marker for survival in multiple myeloma (MM). Here, we present a single institution's experience assessing MRD by NGS of Ig genes and the long-term impact of depth of response as well as clonal diversity on the clinical outcome of a large population of MM patients; 482 MM patients at the University of California, San Francisco (UCSF) diagnosed from 2008 to 2020 were analyzed retrospectively. MRD assessment was performed by NGS.

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This study discusses the importance of minimal residual disease (MRD) detection in acute myeloid leukemia (AML) patients using liquid biopsy and next-generation sequencing (NGS). AML prognosis is based on various factors, including genetic alterations. NGS has revealed the molecular complexity of AML and helped refine risk stratification and personalized therapies.

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