Publications by authors named "S Doelvik"
Purpose: Biomimetic agents are being researched for their potential to stimulate bone formation and boost bone-implant contact. The objective of this study was to assess how osseointegration of dental implants is impacted by platelet-rich fibrin.
Materials And Methods: The present study was a randomized clinical trial with a split mouth design.
Purpose: Acrylic dentures fabricated using polymethyl methacrylate are subjected to either intraoral fatigue stress or extraoral impact stress, eventually forming microcracks and fractures. This limitation should be overcome by either modification in the acrylic resin material or in polymerization techniques. This study compares the impact strength and flexural strength of high-impact resin to conventional resin in short- and long-heat polymerization settings.
View Article and Find Full Text PDFCancer continues to pose a formidable challenge in global health due to its incidence and increasing resistance to conventional therapies. A key factor driving this resistance is tumor hypoxia, characterized by reduced oxygen levels within cancer cells. This hypoxic environment triggers a variety of adaptive mechanisms, significantly compromising the efficacy of cancer treatments.
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- RbgA is a GTPase that plays a crucial role in the maturation of the 50S ribosomal subunit, favoring its GTP-bound state over the GDP-bound state due to conformational differences.
- All-atom molecular dynamics simulations revealed significant conformational changes in RbgA depending on the bound nucleotide, particularly under GTP-Mg and GMPPNP-Mg conditions, which may impact its function.
- The study identifies key regions that influence RbgA's ribosome association and suggests that understanding these mechanisms can help develop new chemical agents to regulate ribosome biogenesis.
Over the last decade, the environmental and wellness cost of antibiotic drug resistance to the societies have been astounding and require urgent attention Metal oxide nanomaterials have been achieved a pull-on deal with its entire applications in biological and photocatalytic applications. The present study conducts a comparative investigation on chemical and biogenic synthesis of zirconium dioxide (ZrO) nanoparticles aimed at enhancing their efficacy in their applications. The plant extract of Passiflora edulis act as a reducing and capping properties offering a sustainable and eco-friendly alternative.
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