Publications by authors named "S Dodangeh"
Obesity is a pandemic problem that correlates with a cluster of metabolic factors leading to poor cardiovascular outcomes, morbidity, and an increased risk of overall mortality. It is necessary to approach obesity with a comprehensive treatment plan, which may involve lifestyle modifications (diet, exercise, and behavioral therapy) and pharmacological interventions. This article provides an overview of the mechanisms of action, efficacy, and safety of available long-term anti-obesity drugs and introduces other potential agents under investigation.
View Article and Find Full Text PDFBackground: St-elevation myocardial infarction (STEMI) is a serious condition that occurs when the blood flow to one or more coronary arteries is blocked, leading to damage or death of the heart muscle (myocardial injury or necrosis). The present study aimed to compare QTc and QTd intervals in patients with STEMI before and 90 minutes after treatment in Booali Sina Hospital, Qazvin, Iran.
Methods: The present study is an analytical cross-sectional study.
Article Synopsis
- - The study analyzed clinical and laboratory findings of multisystem inflammatory syndrome in children (MIS-C) related to COVID-19 in a tertiary children's hospital in Northwest Iran from 2020 to 2022, including 300 pediatric patients following CDC guidelines.
- - A median age of 3 years was noted, with key affected systems being hematological (87%), gastrointestinal (85%), and respiratory (67%), and common elevated inflammatory markers included D-dimer (83.3%) and ferritin (71.4%).
- - The outcomes showed that 81.7% of patients were isolated during hospitalization, 18.3% required ICU care, and 1% died; the study emphasizes the need for echocardiography
Article Synopsis
- Non-ST-elevation myocardial infarction (NSTEMI) is more common than ST-segment elevation myocardial infarction (STEMI) in acute coronary syndrome, and the research aimed to evaluate the role of prolonged QTc interval as a risk factor for NSTEMI patients.
- A cross-sectional study at Bu-Ali Hospital involved 60 NSTEMI patients, measuring their QT intervals and calculating their GRACE scores to assess the relationship between these factors.
- The findings indicated a significant positive correlation between the QTc interval and GRACE score, suggesting that QTc can be a reliable predictor of mortality in NSTEMI patients.
Structural Prediction and Antigenic Analysis of ROP18, MIC4, and SAG1 Proteins to Improve Vaccine Design against Toxoplasma gondii: An In silico Approach.
Infect Disord Drug Targets
September 2024
Background: Toxoplasmosis is a cosmopolitan infectious disease in warm-blooded mammals that poses a serious worldwide threat due to the lack of effective medications and vaccines.
Aims: The purpose of this study was to design a multi-epitope vaccine using several bioinfor-matics approaches against the antigens of Toxoplasma gondii (T. gondii).