Publications by authors named "S Di Lollo"
Article Synopsis
- Long COVID is a significant public health issue affecting many individuals, with this study aiming to identify predictors of its development and specific symptoms over time.
- The study involved over 1,000 hospitalized COVID-19 patients in Italy, using structured phone questionnaires to assess long COVID incidence and symptoms after a median follow-up of 19 months.
- Results indicated that 91.7% experienced long COVID, particularly affecting respiratory and neurological systems, with vaccination reducing symptom odds and Delta variant infection greatly increasing the risk for neuropsychiatric symptoms.
Objective: Determinants of the increased risk of diffuse large B-cell lymphoma (DLBCL) in SLE are unclear. Using data from a recent lymphoma genome-wide association study (GWAS), we assessed whether certain lupus-related single nucleotide polymorphisms (SNPs) were also associated with DLBCL.
Methods: GWAS data on European Caucasians from the International Lymphoma Epidemiology Consortium (InterLymph) provided a total of 3857 DLBCL cases and 7666 general-population controls.
Article Synopsis
- Evidence from previous studies hints that longer telomeres in blood cells could raise the risk of non-Hodgkin lymphoma (NHL), but these studies may have biases and miss key timing for measuring telomere length.
- Researchers analyzed data from over 10,000 NHL cases and 9,562 controls, using a genetic risk score based on telomere-related gene variants to estimate telomere lengths.
- Their findings showed a notable association between longer telomeres and NHL risk, especially for chronic lymphocytic leukemia/small lymphocytic lymphoma, suggesting genetic factors tied to longer telomeres could increase the risk of developing NHL.
Background: Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide polymorphisms (SNPs) for cancer at 13 anatomical sites.
Methods: Between 2007 and 2014, the US National Cancer Institute has generated data from genome-wide association studies (GWAS) for 49 492 cancer case patients and 34 131 control patients.
In Hodgkin Lymphoma (HL), about 20% of patients still have relapsed/refractory disease and late toxic effects rate continue to rise with time. 'Early FDG-PET' and tissue macrophage infiltration (TAM) emerged as powerful prognostic predictors. The primary endpoint was to investigate the prognostic role of both early FDG-PET and TAM; the secondary endpoint was to test if early FDG-PET positivity could correlate with high TAM score.
View Article and Find Full Text PDF