Publications by authors named "S Dhoat"
Background: Atopic eczema is a common, chronic, inflammatory skin condition with considerable heterogeneity. South Asian people living in the UK frequently have low serum vitamin D3 (25(OH)D), and those with atopic disease can present with severe eczema. The association between vitamin D deficiency and eczema severity, and the role of vitamin D supplementation in atopic eczema is inconsistent, and under-researched in people with Asian ancestry.
View Article and Find Full Text PDFCongenital cutaneous mastocytoma is an uncommon disorder characterized by abnormal proliferation of mast cells. It typically presents as a single, small, yellowish-brown plaque, and its diagnosis is generally facilitated by distinctive clinical features, including a positive Darrier's sign. This report presents a case of an unusually large, solitary congenital mastocytoma encompassing nearly the entire circumference of the calf, observed in a newborn boy of Bangladeshi origin.
View Article and Find Full Text PDFArticle Synopsis
- Hyperlinear palms, particularly the 'prominent diamond' pattern, are linked to loss-of-function (LoF) variants in the filaggrin (FLG) gene among young participants with atopic eczema of Bangladeshi descent in East London.
- The study, conducted on 506 participants, identified five distinct palm patterns and found that these patterns correlate with eczema severity (EASI), skin hydration (SH), and transepidermal water loss (TEWL).
- Results suggest that specific palm patterns can effectively indicate the presence of LoF FLG variants, with the most significant predictive ability seen in patterns such as fine perpendicular/prominent diamonds.