Publications by authors named "S Desphande"

Background: Despite strong and growing interest in ending the ongoing opioid health crisis, there has been limited success in reducing the prevalence of opioid addiction and the number of deaths associated with opioid overdoses. Further, 1 explanation for this is that existing interventions target those who are opiate-dependent but do not prevent opioid-naïve patients from becoming addicted.

Objective: Leveraging behavioral economics at the patient level could help patients successfully use, discontinue, and dispose of their opioid medications in an acute pain setting.

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Early tracheal extubation has become common after cardiac surgery. Anesthetic techniques designed to achieve this goal can make immediate postoperative analgesia challenging. We conducted this randomized, placebo-controlled, double-blind study to investigate the effect of a parasternal block on postoperative analgesia, respiratory function, and extubation times.

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Article Synopsis
  • The study tested the effect of initial phase polarity on the Defibrillation Threshold (DFT) in two types of implanted defibrillators (ICDs) in patients with ventricular tachycardia or fibrillation.
  • Patients receiving the Medtronic PCD 7219C showed significantly lower DFT with one polarity (RV+) compared to the other (RV-), while the PCD 7219D group showed a similar trend that wasn't statistically significant.
  • Overall, the results suggest that adjusting the initial phase polarity of the biphasic shock waveform during ICD implantation can influence the DFT, highlighting its importance in optimizing defibrillator performance.
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Plasma cell granuloma of the lung is an uncommon, slow-growing, benign "pseudotumor" morphologically and clinically distinct from malignant plasma cell tumor (plasmacytoma). Its histopathology is distinct from sclerosing hemangioma and pseudolymphoma. Most are located in lung parenchyma, but a few present as endobronchial lesions.

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