Publications by authors named "S Deprez"

Objectives: We evaluated the performance of a novel flow cell morphology analyzer AUTION EYE AI-4510 for counting particles in urine.

Methods: Analytical performance was assessed according to the EFLM European Urinalysis Guideline 2023. Trueness was compared by analyzing 1.

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Background: Hippocampal avoidance during prophylactic cranial irradiation (HA-PCI) is proposed to reduce neurocognitive decline, while preserving the benefits of PCI. We evaluated whether (HA-)PCI induces changes in white matter (WM) microstructure and whether sparing the hippocampus has an impact on preserving brain network topology. Additionally, we evaluated associations between topological metrics with hippocampal volume and neuropsychological outcomes.

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Article Synopsis
  • An SVM-based method was developed to establish pseudo-reference regions in brain PET scans, aimed at minimizing variability across scans and subjects.
  • The method utilized PET datasets from various groups to train a classifier and identify key brain regions for classification, which were tested in three different cohorts using distinct PET tracers.
  • Results showed that the cerebellum, brainstem, subcortical white matter, and temporal cortex consistently emerged as pseudo-reference regions, indicating the approach's reliability even with fewer subjects and across different tracers.
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Purpose: Cancer-related cognitive impairment (CRCI) has been associated with altered brain activation after chemotherapy in areas related to working memory. Hence, improving working memory capacity and associated brain activation might aid in the recovery of CRCI. In this study, we investigated the potential of a mindfulness-based intervention (MBI) to impact working memory-related brain activation.

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Background: Previous case studies have provided evidence for chemotherapy-induced leukoencephalopathy in patients with breast cancer. However, prospective research is lacking. Hence, we investigated leukoencephalopathy before and after chemotherapy and its association with a serum neuroaxonal damage marker.

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