Publications by authors named "S Denizot"

Article Synopsis
  • * Conducted in three maternity wards in France, the research analyzed data from 3,080 neonates, finding a global antibiotic prescription rate of 4.6%, with potential reduction to 1.8% using the PCT algorithm.
  • * Results indicate a 39% relative decrease in antibiotic exposure, suggesting that this PCT-based approach could optimize antibiotic use and minimize overtreatment in newborns, pending validation in larger studies.
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Objectives: The principal aim was to investigate the feasibility of assessing mother-infant interactions at discharge and at 6 months infant corrected age in singletons born before 32 weeks of gestation. The secondary aims were to describe these interactions and their disorders, explore the association between maternal emotional state and the interactions, and assess the relationship between disordered interactions and infant social withdrawal behaviour.

Methods: OLIMPE is an ancillary study of the population-based study EPIPAGE 2, which recruited preterm neonates in France in 2011.

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Fetal inflammatory response syndrome is implicated as a cause of fetal or neonatal injury. We analyzed the relationship between the procalcitonin umbilical cord blood level and neonatal outcome. A total of 237 preterms born in a level III perinatal medicine unit of a French university hospital were enrolled in a prospective observational study.

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Background: Bilirubin-related neurotoxicity is an important clinical issue in very low birthweight (VLBW) infants, and the existing literature is inconsistent.

Objective: To analyze the relationship between maximal serum unconjugated bilirubin levels (SBL) and neurodevelopmental outcome at 2-year corrected age in VLBW infants.

Methods: Phototherapy was initiated in all infants born before 33 weeks of gestation, according to Maisels' recommendations.

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This article describes a study of procalcitonin (PCT) measured in cord blood as a discriminating marker of early-onset neonatal infection. This was a monocenter retrospective study with prospective collection of data including all babies born during the study period. Those presenting infection risk factors had PCT measurement.

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