Publications by authors named "S Denfield"
Purpose: Echocardiography is considered essential during cannulation placement and manipulations. Literature evaluating transthoracic echocardiography (TTE) usage during pediatric VV-ECMO is scant. The purpose of this study is to describe the use of echocardiography during VV-ECMO at a large, quaternary children's hospital.
View Article and Find Full Text PDFBackground: PRDM16 plays a role in myocardial development through TGF-β (transforming growth factor-beta) signaling. Recent evidence suggests that loss of PRDM16 expression is associated with cardiomyopathy development in mice, although its role in human cardiomyopathy development is unclear. This study aims to determine the impact of PRDM16 loss-of-function variants on cardiomyopathy in humans.
View Article and Find Full Text PDFArticle Synopsis
- Arrhythmogenic cardiomyopathy (AC) is a heart disease that causes issues with how heart cells work together, leading to arrhythmias, or irregular heartbeats.
- It was originally believed to mainly affect the right ventricle, but newer studies show it can impact both ventricles or just the left ventricle.
- The review discusses the growth in knowledge regarding AC's epidemiology, causes, symptoms, diagnosis, and treatment across different age groups.
Background: The significance of atypical infiltrates (eosinophils or plasma cells) on endomyocardial biopsy (EMB) after pediatric heart transplant (HTx) is not known. We hypothesized that atypical infiltrates are associated with worse post-HTx outcomes.
Methods: We performed a retrospective cohort study of consecutive patients <21 years old who underwent primary HTx between 2013 and 2017.