Publications by authors named "S Demirkaya"
Background: Cognitive-motor dual-task walking results a decrease in walking performance of patients with multiple sclerosis (PwMS) and it is known as dual-task cost (DTC). However, there is a lack of evidence about the effects of dual-tasks with hierarchical difficulty on DTC in PwMS.
Research Question: This study aimed to investigate the effect of task difficulty on DTC during cognitive-motor dual-task walking in people with multiple sclerosis (PwMS).
Burn injuries are a serious emergency. Most burn injuries in children can be treated as outpatients. The aim of this study was to present the clinical and epidemiologic characteristics of pediatric burn injuries treated in our outpatient burn clinic.
View Article and Find Full Text PDFOmega fatty acid ratios and neurodegeneration in a healthy environment.
Prostaglandins Other Lipid Mediat
February 2024
Article Synopsis
- Neurodegenerative diseases like Alzheimer's and Parkinson's present major public health challenges, with both genetic and environmental factors, particularly diet and lifestyle, playing a role.
- This study investigates how Omega-3 and Omega-6 fatty acids affect neuroinflammation using BV-2 microglial cells, examining cell viability, cytokine production, and cellular changes based on different fatty acid ratios.
- Findings indicate that a 2/1 Omega-6 to Omega-3 ratio decreases cell viability while altering cytokine secretion, revealing complex interactions that could influence neuroinflammatory processes and suggesting a need for further research into their implications for neurodegenerative diseases.
Exploring the role of polyunsaturated fatty acid ratios in modulating neuroinflammation in LPS-induced microglia: A comprehensive in vitro analysis.
Prostaglandins Other Lipid Mediat
October 2023
Article Synopsis
- - The study explored how different ratios of omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) affect microglial cells, which are important for immune response in the brain, when induced by lipopolysaccharide (LPS).
- - Results indicated that specific PUFA ratios, particularly 7/1 and 2/1 ω-6/ω-3, led to more active microglial shapes and reduced secretion of tumor necrosis factor (TNF)-α compared to the control group.
- - The findings suggest that optimizing ω-6/ω-3 intake ratios could be beneficial for managing neuroinflammation and developing dietary strategies
Purpose: The aim of this study is to evaluate the prevalence of anxiety disorders, its correlation with sociodemographic characteristics, its comorbidities with other psychiatric disorders and its predictors in school-aged children.
Methods: This study is part of a representative, multi-centered national study that is planned by the Turkish Association of Child and Adolescent Mental Health to evaluate the prevalence of psychopathology among elementary school students in Turkey between the years 2014-2015. Children are screened via Kiddie Schedule for Affective Disorders and Schizophrenia for School Age Children Present and Lifetime Version.