Publications by authors named "S Demirhan"
Clinical Outcomes of Oral Antibiotic Switch in Children with Staphylococcus aureus Bacteremia.
Turk Arch Pediatr
September 2024
Article Synopsis
- The study investigated pediatric Staphylococcus aureus bacteremia (SAB), focusing on causes, treatment management, and outcomes, particularly the transition to oral antibiotics.
- Over five years, 88 episodes of SAB were analyzed, primarily linked to central line infections and osteoarticular conditions; 45.5% of cases transitioned to oral antibiotics after intravenous treatment.
- Results showed low 30-day mortality and recurrence rates, with no poor outcomes in patients who switched to oral therapy, suggesting its safety for select pediatric patients.
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a clinical challenge in selecting empiric antimicrobials for pediatric infections. We implemented nasal MRSA polymerase chain reaction (nMRSA PCR) screening as a diagnostic tool and evaluated its impact on empiric antibiotic use and clinical outcomes.
Methods: A retrospective single-center study of patients hospitalized with infections who were empirically prescribed anti-MRSA antibiotics was conducted prior to and following the initiation of nMRSA PCR screening.
Background: Valganciclovir is the only approved antiviral for cytomegalovirus (CMV) prevention in pediatric solid organ transplantation (SOT). Additional approaches may be needed to improve outcomes.
Methods: A multicenter retrospective study from 2016 to 2019 was conducted of pediatric SOT recipients in whom at least 3 months of valganciclovir prophylaxis was planned.
Background: Pediatric actinomycosis studies are limited to case reports or small case series. In this retrospective cohort study, we aimed to describe characteristics of skin and soft tissue actinomycosis in adolescents and children.
Methods: We conducted the study from January 2019 to December 2022, including patients ≤21 years of age with at least 1-year follow-up data.