Publications by authors named "S Delaine"

Article Synopsis
  • The study is testing a drug called regorafenib combined with a chemotherapy treatment called FOLFIRINOX for patients with a specific type of cancer that has certain genetic changes (RAS mutations).
  • They want to find out how safe this treatment is and how well it works over time.
  • This trial will include different groups of patients, and they will check how many people respond to the treatment over a period of 48 weeks.
View Article and Find Full Text PDF

Purpose: Sexual quality of life (QoL) is affected during and after breast cancer (BC) treatment and is not specifically evaluated with the general health-related quality-of-life questionnaires EORTC QLQ-C30 or QLQ-BR23. A specific questionnaire, the EORTC SHQ-C22, including physical, psychological, and social aspects of sexuality, was recently developed to address this issue in cancer patients.

Methods: A prospective bicentric study was conducted to evaluate the sexual QoL of women with BC during the first year of adjuvant hormonal treatment.

View Article and Find Full Text PDF

Background: Malignant peritoneal mesothelioma (MPM) is a rare tumoral disease characterized by the diffuse involvement of the peritoneal serosa. The standard frontline treatment of MPM is cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) unless the peritoneal disease is considered unresectable. For unresectable patients the standard frontline treatment is a combination of cisplatin and pemetrexed but the prognosis remains ominous with only 13 months of overall survival (OS).

View Article and Find Full Text PDF

To explain missing data in a study of 83 older adults, hypotheses regarding fatigue and age were proposed, the former (fatigue) appearing more likely.

View Article and Find Full Text PDF

Purpose: The identification of nursing home residents who can continue to participate in advance care planning about end-of-life care is a critical clinical and bioethical issue. This study uses high quality observational research to identify correlates of advance care planning in nursing homes, including objective measurement of capacity.

Design And Methods: The authors used cross-sectional, cohort study between 1997 and 1999.

View Article and Find Full Text PDF