Publications by authors named "S Del Curto"

Article Synopsis
  • Hyperthermia treatment's effectiveness relies on achieving specific temperatures in targeted areas, requiring systems to provide controlled and conformal heating.
  • The study involved six European institutions testing BSD-Sigma 60 and Sigma Eye devices, measuring thermal distribution after heating with a total power of 1000 watts in standardized phantoms.
  • Results indicated that most applicators achieved the desired temperature increase, with minor deviations in focus location and symmetry, leading to proposed minimum acceptable values for quality metrics and recommendations for future quality assurance in hyperthermia applications.
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Article Synopsis
  • - A new system called the thermobrachytherapy (TBT) prototype has been developed to combine interstitial hyperthermia with high-dose-rate brachytherapy (HDR-BT), aiming to improve treatment effectiveness in cancer therapy.
  • - The TBT system includes sophisticated components like radiofrequency power delivery and dual-function applicators, and has been tested for efficiency, heating capacity, and temperature regulation through a series of experiments.
  • - Results showed that the TBT prototype met necessary requirements, achieving a 50% heating efficiency with a 6°C increase in temperature in 6 minutes, and is ready for further validation testing and potential clinical applications.
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The unexpected 4,1-hydroaminoalkylation of dienes provides selective access to linear homoallylic amines by zirconium catalysis. This switch from the traditional branched preferred regioselectivity to selective linear product formation using this early transition metal can be attributed to π-allyl intermediates. The reactivity of these isolated intermediates on a sterically accessible and coordinatively flexible chelating bis(ureate) Zr(iv) complex confirmed reversible C-C bond formation in hydroaminoalkylation catalysis.

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Objective: To investigate fear of hypoglycemia (FoH) in parents of children with type 1 diabetes (T1D) before and after undergoing training to learn intranasal (IN) glucagon administration.

Method: In this pre-test/post-test uncontrolled study 364 caregivers of patients with T1D (6-18 years) completed questionnaires measuring sociodemographic characteristics, diabetes-related factors (e.g.

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Background: The relationship between Helicobacter-pylori(Hp)infection and inflammatory-bowel-disease(IBD) in pediatric-patients remains controversial. We aimed to assess the Hp-infection occurrence in newly-diagnosed pediatric-patients with IBD compared to no-IBD patients. Additionally, we aimed to examine differences in clinical-activity-index(CAI) and endoscopic-severity-score(ESS)between IBD-patients with and without Hp-infection, at baseline and at 1-year-follow-up(FU), after eradication-therapy(ET).

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