Publications by authors named "S Deidda"
Article Synopsis
- The study aims to provide updated evidence for managing stage I colon cancer (CC) post-surgery, focusing on recurrence rates and risk factors.
- Despite low recurrence risk, some guidelines suggest intensive follow-up is unnecessary, but data on actual recurrence rates is limited.
- The findings reveal a 5% recurrence rate, primarily systemic, with significant risk factors including tumor characteristics and patient demographics, suggesting a need for improved postoperative follow-up strategies.
Background: Diverting ileostomy is a common procedure in rectal cancer surgery, but it is sometimes associated with a nonnegligible rate of complications. The primary aim of this study was to analyze the incidence and types of stoma-related complications for ileostomy creation after rectal cancer resection. The secondary aims were to report the indications, the technical details, and the efficacy of stoma care provided by ostomy nurses.
View Article and Find Full Text PDFBackground: Antibody-mediated rejection is a significant cause of kidney transplant failure. Recent studies have shown that the MHC class I gene influences the transplantation outcome. However, the role of the primary receptor, NKG2D, has yet to be explored.
View Article and Find Full Text PDFColorectal cancer (CRC) is a leading tumor worldwide. In CRC, the angiogenic pathway plays a crucial role in cancer development and the process of metastasis. Thus, anti-angiogenic drugs represent a milestone for metastatic CRC (mCRC) treatment and lead to significant improvement of clinical outcomes.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the effectiveness and feasibility of rectal-sparing treatments for rectal cancer patients who showed a significant response after neoadjuvant therapy, although there is ongoing debate about their effectiveness.
- In a multicenter study involving 178 patients, around 80.9% were able to preserve their rectum while showing promising survival rates over three years, including an overall survival rate of 80.6% and a stoma-free survival rate of 95%.
- The findings suggest that for rectal cancer patients who achieve a major or complete response to neoadjuvant therapy, rectal preservation is possible in most cases without negatively affecting patient outcomes.