Publications by authors named "S De-Franco"

Purpose Of The Study: Hand enchondromas are benign cartilage bone tumors. Curettage represents the actual gold standard for hand enchondromas. Little has been written about the effectiveness of curettage on hand functionality.

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Introduction: Periprosthetic joint infection (PJI) represents a serious burden in orthopaedic oncology. Through the years, several local expedients have been proposed to minimise the risk of periprosthetic infection. In this study, we report our outcomes using topical vancomycin powder (VP) with the aim to prevent PJIs.

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Introduction: Insomnia causes serious adverse health effects and is estimated to affect 10-30% of the worldwide population. This study leverages personalized fine-tuned machine learning algorithms to detect insomnia risk based on questionnaire and longitudinal objective sleep data collected by a smart bed platform.

Methods: Users of the Sleep Number smart bed were invited to participate in an IRB approved study which required them to respond to four questionnaires (which included the Insomnia Severity Index; ISI) administered 6 weeks apart from each other in the period from November 2021 to March 2022.

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Article Synopsis
  • The Arabidopsis splicing factor SR45 plays a critical role in various biological processes, and its loss results in several developmental abnormalities, including delayed root growth and altered flower structures.
  • The study investigates the functions of the different domains in SR45, focusing on its expression patterns, nuclear localization, and interaction with other proteins and RNA.
  • Results reveal that SR45 localizes in the nucleus, has a specific RNA binding capacity, and connects vital mRNA splicing and surveillance systems, highlighting the importance of its domains in forming spliceosomal and exon-exon junction complex assemblies.
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Background: Aneurysmal bone cysts (ABCs) are benign but locally aggressive cystic lesions of the bone. Pelvic ABCs are extremely rare and hard to treat due to their high risk of local recurrence and the tough access to pelvic bones.

Methods: In this retrospective study, we evaluated pediatric cases with pelvic ABC treated with curettage, cryotherapy and bone grafting treated in our institution between 2016 and 2022.

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