[Medical treatment of early spontaneous miscarriages: a prospective study of outpatient management using misoprostol].

Objectives: Medical treatment using misoprostol has been recommended as an alternative to surgical evacuation for spontaneous miscarriages in the first trimester, in order to avoid anesthesia, a surgical operation and hospitalization. Our aim was to assess the efficacy and the safety of vaginal misoprostol in out-patient management of early miscarriages.

Material And Methods: We conducted a prospective cohort study including patients with a spontaneous miscarriage of less than 14 weeks gestation.

[Complications of vacuum extractor deliveries].

Objectives: To describe maternal and neonatal complications following deliveries assisted by vacuum extraction and to compare outcomes with those obtained after spontaneous vaginal delivery. We wanted to know if vacuum extractor was a risk factor by itself.

Materials And Methods: We conducted a retrospective study of two years activity involving 4524 deliveries of which 845 (18.

Evaluation of enkephalinase inhibition in the living mouse, using [3H]acetorphan as a probe.

A novel in vivo binding test was developed in order to evaluate the degree of occupancy of enkephalinase (EC 3.4.24.

Labelling and exploration of the active site of enkephalinase (EC 3.4.24.11) in kidney membranes with [3H]thiorphan as ligand.

[3H]Thiorphan, a potent inhibitor of enkephalinase (EC 3.4.24.

Characterisation of two probes for the localisation of enkephalinase in rat brain: [3H]thiorphan and a 125I-labeled monoclonal antibody.

We studied the binding of two radioactive probes, i.e. [3H]thiorphan and a 125I-labeled monoclonal antibody raised against the rabbit kidney enzyme, to enkephalinase (EC 3.