Publications by authors named "S De La Barrera"
The pharmaceutical industry has been primarily focused on developing synthetic drugs to address orofacial pain (OFP)-related conditions. There is limited knowledge regarding the efficacy of the use of herbal extracts in treating OFP. A systematic review and a meta-analysis of 62 randomized controlled trials assessing the analgesic effects of herbal extracts on pain intensity in various orofacial conditions was conducted.
View Article and Find Full Text PDFBackground/objectives: Nutritional deficiencies have been proposed as possible etiological causes for autoimmune diseases, among which type 1 diabetes (T1D). Vitamin K (VK) has potentially positive effects on type 2 diabetes, but its role on T1D in humans remains largely unknown. We aimed to examine the presence of a causal association between VK and T1D using a Mendelian randomization (MR) approach.
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- An elevated lactate/albumin ratio (LAR) greater than 0.5 in critically ill pediatric patients is linked to higher mortality and microcirculation issues, particularly in children with sepsis.
- In a study involving 178 children admitted to the PICU, those with septic shock showed significantly higher chances of having an elevated LAR and more microvascular blood flow abnormalities.
- The findings suggest that a normal LAR indicates less risk of microcirculatory injury, making LAR a valuable biomarker for assessing sepsis-related complications in pediatric patients.
Food addiction, or ultra-processed food addiction (UPFA), has emerged as a reliable and validated clinical entity that is especially common in individuals seeking treatment for eating disorders (EDs), substance use disorders (SUDs) and co-occurring psychiatric disorders (including mood, anxiety and trauma-related disorders). The clinical science of UPFA has relied on the development and proven reliability of the Yale Food Addiction Scale (YFAS), or subsequent versions, e.g.
View Article and Find Full Text PDFMyhre syndrome (MS) is a rare genetic condition that presents with multiple genetic anomalies including cleft lip and palate and Eustachian tube dysfunction. These patients are at a high risk for airway scarring from intubation and mucosal inflammation. Hearing loss (conductive or mixed, of varying severity) is a common comorbidity in these patients, the exact etiology of which is still unclear.
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