Guardians of consent: enhancing rape prevention through social control mechanisms.

Introduction: Rape is a severe violation involving non-consensual sexual acts, often accompanied by force, threats, or coercion, leading to profound physical, emotional, and social consequences for survivors.

Aim: This review aims to examine and synthesize research on effective strategies for rape prevention and intervention, with a particular focus on social control mechanisms, legal frameworks, cultural change, educational programs, public awareness campaigns, community vigilance, victim support services, and the influence of digital media.

Methodology: A comprehensive review was conducted by searching PubMed, Scopus, PsycINFO, and Google Scholar for peer-reviewed articles, policy papers, and reports from the past 20 years.

Lotus seed extract: anticancer potential and chemoprofiling by , and GC-MS studies.

Lotus seeds, also known as Nelumbinis semen, has been utilized for over 7,000 years as vegetable, functional food and medicine. In this study, we primarily investigated the anticancer effects of lotus seed extracts, particularly of the methanolic extract (MELS) on cell proliferation inhibition, apoptosis induction and cell cycle arrest in ovarian cancer cell lines. Further, we studied the phytochemical composition of the MELS by gas chromatography-mass spectrometry (GC-MS) analysis.

Speed of innovation: how quickly are different therapeutic areas adopting paradigm-shifting drugs?

The past decades have seen breakthroughs in drug discovery that have revolutionized the treatment of many diseases. These paradigm-shifting treatments are often novel targeted therapies, directed at new areas of biology. To better understand these paradigm shifts, we conducted an analysis of the adoption of 25 drug classes from five major therapeutic areas (TAs).

Cost-effectiveness of FRAX®-based intervention thresholds for management of osteoporosis in Indian women: a Markov microsimulation model analysis.

Unlabelled: A cost-effectiveness analysis of FRAX® intervention thresholds (ITs) in Indian women over 50 years indicated that generic alendronate was cost-effective for age-dependent major osteoporotic fracture (MOF) ITs and hip fracture (HF) ITs starting at ages 60 and 65 years for full and real-world adherence, respectively. Alendronate was cost-effective at fixed MOF IT of 14% and HF IT of 3.5%, regardless of age.

Dynamic patterns in herding predator-prey system: Analyzing the impact of inertial delays and harvesting.

This study expands traditional reaction-diffusion models by incorporating hyperbolic dynamics to explore the effects of inertial delays on pattern formation. The kinetic system considers a harvested predator-prey model where predator and prey populations gather in herds. Diffusion and inertial effects are subsequently introduced.