Publications by authors named "S Dardenne"
Background: Frailty and cognitive impairment are common manifestations of the ageing process and are closely related. But the mechanisms linking aging, physical frailty, and cognitive disorders, are complex and remain unclear.
Objectives: We aim to explore the role of cerebral amyloid pathology, but also a range of nutritional, physical, biological or brain-aging marker in the development of cognitive frailty.
Background: Chemotherapy is increasingly used before hepatic resection, with controversial impact regarding liver function. This study aimed to assess the capacity of 99mTc-labelled-mebrofenin SPECT-hepatobiliary scintigraphy (HBS) to predict liver dysfunction due to chemotherapy and/or chemotherapeutic-associated liver injuries (CALI), such as sinusoidal obstruction syndrome (SOS) and nonalcoholic steatohepatitis (NASH) activity score (NAS).
Methods: From 2011 to 2015, all consecutive noncirrhotic patients scheduled for a major hepatectomy (≥ 3 segments) gave informed consent for preoperative SPECT-HBS allowing measurements of segmental liver function.
Article Synopsis
- The study investigates the role of the cystine/glutamate antiporter system (xCT) as a potential target for treating epilepsy, focusing on its influence on glutamate levels and neuroinflammation.
- Experiments were conducted using xCT knockout mice and control mice, where various epilepsy models were tested, including self-sustained status epilepticus and corneal kindling.
- Results indicated that xCT knockout mice had delayed epilepsy development, fewer seizures, and reduced neuroinflammation, suggesting that xCT may play a protective role in the context of epilepsy.
Background: Subjective cognitive decline (SCD) may be a very early symptom of Alzheimer's disease (AD) and may be associated with a cognitive decline in a cognitively normal population. The McNair and Kahn Scale was used to assess memory complaints in the GuidAge study.
Objective: Our objectives were to examine if the McNair and Kahn Scale can predict cognitive decline and to screen which (if any) of the question(s) of this scale would better predict this cognitive decline.
Context: Acute pancreatitis is often caused by acute alcoholic intoxication or biliary stone migration. Other etiologies are less frequent.
Case Report: We report an exceptional case of kissing ulcer as the cause of an acute pancreatitis due to the perforation of the posterior ulcus into the pancreas.