PRE-HOSPITAL EMERGENCY MEDICAL SERVICES FOR ELDERLY POPULATION IN TBILISI.

The importance of the issue is determined by the current demographic situation in Georgia and the world in general. The trend of growing the number of older people and the increase of the life span is obvious. At the same time in the number of countries, particularly in the developed western countries and Japan, the decrease of birth rate is noticed.

Treatment characteristics in elderly.

The pharmacodynamics and pharmacokinetics of medications, their therapeutic and toxic effects are age dependant. In the treatment of old people polypharmacy is widely used. The most common results of polypharmacy are increased adverse drug reactions, drug-drug interactions.

Age-related changes of sex hormones--level among males in populations with high index of longevity.

The phenomenon of longevity as a kind of model of "physiological" aging has been the main research subject of the Department of Gerontology Institute of Morphology (Georgia) since 1970. The researches were conducted under the Multiplan complex program "Bio-anthropological and social and ethnic investigation of nations and ethnic groups with high index of longevity" in the "long-liver" populations of Georgia. The research aimed at studying the changes in the content of the sex steroids and gonadotrophic hormones in the blood plasma of the healthy men aged from 45 to 90 and more years and residing in Georgia.

A population genetic study in the Ochamchir region, Abkhazia, SSR.

The reported longevity of residents of the Soviet Socialist Republic of the Caucasus has focused considerable attention on this population. However, little is known of the genetic composition of this population. With this in mind, several village populations of the Ochamchir Region, Abkhazia, SSR, were typed for 37 discrete genetic blood groups, erythrocyte and plasma protein loci.

Genetic study of high longevity index populations.

Five-year multidisciplinary study of longevity in the Georgian SSR made it possible to select two populations (Abkhazian and Imeretian), in which indices of longevity were much higher, than the average level for the rural population of the whole region. The distribution of polymorphic systems of red cell enzymes (adenilate kinase, esterase D, phosphoglucomutase I, acid phosphatase, 6-phosphogluconate dehydrogenase, glyoxalase I, lactate dehydrogenase, adenosine deaminase, glutamate pyruvate transaminase, phosphoglycolate phosphatase, phosphohexose isomerase) and serum proteins (haptoglobin, Gc-component and transferrin) was studied for genetic analysis of these populations. The results indicate that for all the studied loci the observed genotypic frequencies in both populations are distributed according to Hardy-Weinberg equilibrium.