SD-OCT imaging of idiopathic macular holes with spontaneous closure.

Spectral-domain optical coherence tomography serial changes in three cases of spontaneous closure of idiopathic macular hole at stages II, III, and IV are described. Initial and serial spectral-domain optical coherence tomography images document the progressive closure. Macular holes apparently resolved spontaneously through two different mechanisms: posterior hyaloid detachment in case 1 and a contraction of epiretinal macular membrane in cases 2 and 3.

Role of the intravitreal growth factors in the pathogenesis of idiopathic epiretinal membrane.

Purpose: The aim of the present study is to evaluate the roles of TGFs β1 and β2, glial cell line-derived neurotrophic factor (GDNF), and nerve growth factor (NGF) in the pathogenesis of idiopathic epiretinal membrane (ERM).

Methods: Eight patients, six males and two females, with an average age of 60.25 ± 17.

Vogt-Koyanagi-Harada syndrome and keratoconjunctivitis sicca.

Purpose: To discover a relationship between Vogt-Koyanagi-Harada (VKH) syndrome and Sjögren syndrome.

Design: Observational case-control study.

Methods: Sixteen Italian patients with VKH syndrome and 16 controls with diffuse uveitis underwent tear analysis and rheumatologic evaluation.

Ibopamine treatment in chronic hypotony secondary to long-lasting uveitis. A case report.

Purpose: To assess the clinical efficacy of ibopamine eye drops in severe hypotony secondary to chronic progressive uveitis.

Methods: Case report. A 47-year-old man with a 37-year history of diffuse uveitis and severe refractory hypotony was treated with topical 2% ibopamine (Trazyl) six times a day.