[Effect of calciferol-protein deficiency on the metabolism of bone collagen].

Growing rats received rations with separate and combined deficiencies of vitamin D, protein and certain essential amino acids, during 60 days. An increment was recorded in the total amount of collagen in the tubular bones at the expense of its mature, insoluble fraction, in the presence of a decreased content of salt- and acid-soluble fractions of this protein. These shifts were more manifest in combined calciferol-protein deficiency.